Manufacture of Microspheres as Carrier Particles for Active Biomolecules
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چکیده
A number of processes are available: condensation-, interfacial-, suspensionand emulsion-polymerization. Suspension and emulsion polymerization are the preferred methods for the commercial production of polymer microsphere carrier particles and reference/standard particles for calibration of scientific instruments. In general, emulsion polymerization produces a smaller particle size and a narrower molecular weight distribution. Both methods are aqueous two-phase batch processes. The use of a double emulsion, e.g water-in-oil-in-water (W/O/W), is a variation of the emulsion polymerization method.
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